Mitragyna speciosa Wikipedia

As of January 2026, 30 states and the District of Columbia regulate kratom. An estimated 1.7 million Americans ages 12 and older used kratom in 2021, according to the Substance Abuse and Mental Health Services Administration's National Survey on Drug Use and Health. The drug is popular, particularly among the college crowd, but can have a number of serious side effects, including liver toxicity and seizures. "We don't want to be caught flat-footed like we did with fentanyl and prescription drugs. This may be the fourth wave of the opioid epidemic." The U.S. Food and Drug Administration is now looking to control the concentrated by-product, 7-OH. The Zen Den sells kratom served in a tea made from kratom tea leaves.

Opia High Potency Classic Mitragynine Tablets 240mg, 4 tablets

Our 2026 state-by-state legality guide is updated as laws change. The FDA has stated repeatedly that 7-OH is not permitted in dietary supplements or conventional foods and that there are no FDA-approved drugs containing it. Our free newsletters deliver Memphis straight to your inbox. Want the latest in local news, events, music and food? Every dollar helps power the newsroom and protect the future of independent media in Memphis. That executive order came with the promise of $50 million to work with states “that have enacted or are developing programs to advance psychedelic drugs for serious mental illnesses.”

Major moments in U.S. kratom policy

• A new, purified compound from kratom called 7-hydroxymitragynine (also known as 7 hydroxy or 7-OH) is now being sold in pill form.
• “It’s caused overdose, death, sickness, hospital visits from people thinking that this is marketed as an energy drink or something to help you with aches and pains,” said FitzGerald.
• The lawsuit asked the court to prohibit the manufacture, distribution and retail sale of kratom and its alkaloids, mitragynine, and 7-OH.
• This approach keeps our products aligned with the regulatory distinction between natural and synthetic, while delivering the potency experienced users seek.

For experienced kratom users seeking targeted effects, 7-OH products for sale offer a more intense experience. Some manufacturers have begun isolating and concentrating 7-OH, creating products with alkaloid levels far beyond what occurs in natural kratom. OPIA Kratom contains 7-Hydroxymitragynine, which is a natural alkaloid that is potent and found in the kratom plant (Mitragyna Speciosa). Check out all of our products, like kratom capsules and 7-Hydroxy tablets, to unlock a naturally better you. As with all kratom products, do not exceed dosing recommendations. While this week’s kratom news focuses on concentrated 7-OH, our whole-leaf powder and capsules remain unaffected.

Be the first to know about new products, promotions, sales, and more! Check out our Blogs for expert guides, wellness tips, and the latest news on Kratom and other natural herbs. The Coleman Institute in Richmond said at the beginning of this year that 75% of their calls were related to kratom and 7-OH. RICHMOND, Va. — Virginia is cracking down on kratom and a stronger chemical compound linked to it after Gov. Abigail Spanberger signed a new bill into law Tuesday. The Rockefeller Institute will continue to monitor the kratom policy landscape as it evolves. Some Wi Doc variations of these kratom consumer protection acts have been introduced this session in states like Hawaii, Idaho, Illinois, Massachusetts, Maryland, Michigan, Ohio, Pennsylvania, Washington, and Wyoming.

• FDA Commissioner Marty Makary, M.D., M.P.H., wrote in a statement that vape stores are “popping up in every neighborhood in America, and many are selling addictive products like concentrated 7-OH.”
• Over time, users can build a tolerance and face withdrawal symptoms, such as insomnia, nausea, muscle pain, irritability and even involuntary jerky movements, according to American Addiction Centers.
• Check out all of our products, like kratom capsules and 7-Hydroxy tablets, to unlock a naturally better you.
• In another study with rats, kratom supplementation suppressed hunger by inhibiting the hypothalamus, the part of the brain responsible for appetite and cravings.
• But in the years since, the popularity of kratom — and its synthetic derivatives — has spread.
• These kratom consumer protection acts dictate how the product is made, how it is marketed, and who is eligible to purchase.
• In a Tuesday press release, the HHS announced that the FDA is recommending a scheduling action to control these products under the Controlled Substances Act (CSA).

SHOP KRATOM BY EFFECT

The FDA also warns people against taking kratom due to side effects such as nausea, constipation, dizziness, liver problems, and, in rare cases, death. Some people have reported that kratom can help with self-treatment of opioid withdrawal symptoms. Some reports suggest that kratom may be an effective treatment for opioid addiction. Very little research has been done on the health effects of kratom.